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TACE Activation by MAPK-Mediated Regulation of Cell Surface Dimerization and TIMP3 Association
Ectodomain shedding mediated by tumor necrosis factor–α (TNF-α)–converting enzyme [TACE; also known as ADAM17 (a disintegrin and metalloproteinase 17)] provides an important switch in regulating cell proliferation, inflammation, and cancer progression. TACE-mediated ectodomain cleavage is activated...
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| Publicado no: | Sci Signal |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254802/ https://ncbi.nlm.nih.gov/pubmed/22550340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002689 |
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