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Post-translational regulation of TGF-β receptor and Smad signaling

TGF-β family signaling through Smads is conceptually a simple and linear signaling pathway, driven by sequential phosphorylation, with type II receptors activating type I receptors, which in turn activate R-Smads. Nevertheless, TGF-β family proteins induce highly complex programs of gene expression...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:FEBS Lett
Main Authors: Xu, Pinglong, Liu, Jianming, Derynck, Rik
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240271/
https://ncbi.nlm.nih.gov/pubmed/22617150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.05.010
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