Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program

Developmental signaling molecules are used for cell fate determination, and understanding how their combinatorial effects produce the variety of cell types in multicellular organisms is a key problem in biology. Here, we demonstrate that the combination of leukemia inhibitory factor (LIF), bone morp...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kime, Cody, Sakaki-Yumoto, Masayo, Goodrich, Leeanne, Hayashi, Yohei, Sami, Salma, Derynck, Rik, Asahi, Michio, Panning, Barbara, Yamanaka, Shinya, Tomoda, Kiichiro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098653/
https://ncbi.nlm.nih.gov/pubmed/27738243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608564113
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