Multi-factor data normalization enables the detection of copy number aberrations in amplicon sequencing data

Motivation: Because of its low cost, amplicon sequencing, also known as ultra-deep targeted sequencing, is now becoming widely used in oncology for detection of actionable mutations, i.e. mutations influencing cell sensitivity to targeted therapies. Amplicon sequencing is based on the polymerase cha...

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Bibliografische gegevens
Gepubliceerd in:Bioinformatics
Hoofdauteurs: Boeva, Valentina, Popova, Tatiana, Lienard, Maxime, Toffoli, Sebastien, Kamal, Maud, Le Tourneau, Christophe, Gentien, David, Servant, Nicolas, Gestraud, Pierre, Rio Frio, Thomas, Hupé, Philippe, Barillot, Emmanuel, Laes, Jean-François
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
Onderwerpen:
Hitseq Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253825/
https://ncbi.nlm.nih.gov/pubmed/25016581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu436
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