Multi-factor data normalization enables the detection of copy number aberrations in amplicon sequencing data

Motivation: Because of its low cost, amplicon sequencing, also known as ultra-deep targeted sequencing, is now becoming widely used in oncology for detection of actionable mutations, i.e. mutations influencing cell sensitivity to targeted therapies. Amplicon sequencing is based on the polymerase cha...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Boeva, Valentina, Popova, Tatiana, Lienard, Maxime, Toffoli, Sebastien, Kamal, Maud, Le Tourneau, Christophe, Gentien, David, Servant, Nicolas, Gestraud, Pierre, Rio Frio, Thomas, Hupé, Philippe, Barillot, Emmanuel, Laes, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Hitseq Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253825/
https://ncbi.nlm.nih.gov/pubmed/25016581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu436
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