Assessing Copy Number Alterations in Targeted, Amplicon-Based Next-Generation Sequencing Data

Changes in gene copy number are important in the setting of precision medicine. Recent studies have established that copy number alterations (CNAs) can be detected in sequencing libraries prepared by hybridization-capture, but there has been comparatively little attention given to CNA assessment in...

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Detalhes bibliográficos
Publicado no:J Mol Diagn
Main Authors: Grasso, Catherine, Butler, Timothy, Rhodes, Katherine, Quist, Michael, Neff, Tanaya L., Moore, Stephen, Tomlins, Scott A., Reinig, Erica, Beadling, Carol, Andersen, Mark, Corless, Christopher L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707205/
https://ncbi.nlm.nih.gov/pubmed/25468433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2014.09.008
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