Clinical Value of EGFR Copy Number Gain Determined by Amplicon-Based Targeted Next Generation Sequencing in Patients with EGFR-Mutated NSCLC

BACKGROUND: The clinical relevance of epidermal growth factor receptor (EGFR) copy number gain in patients with EGFR mutated advanced non-small cell lung cancer on first-line tyrosine kinase inhibitor treatment has not been fully elucidated. OBJECTIVE: We aimed to estimate EGFR copy number gain usin...

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Publicado no:Target Oncol
Main Authors: Wei, Jiacong, Meng, Pei, Terpstra, Miente Martijn, van Rijk, Anke, Tamminga, Menno, Scherpen, Frank, ter Elst, Arja, Alimohamed, Mohamed Z., Johansson, Lennart F., Stigt, Jos, Gijtenbeek, Rolof P. G., van Putten, John, Hiltermann, T. Jeroen N., Groen, Harry J. M., Kok, Klaas, van der Wekken, Anthonie J., van den Berg, Anke
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2021
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935828/
https://ncbi.nlm.nih.gov/pubmed/33606136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-021-00798-2
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