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Assessing Copy Number Alterations in Targeted, Amplicon-Based Next-Generation Sequencing Data

Changes in gene copy number are important in the setting of precision medicine. Recent studies have established that copy number alterations (CNAs) can be detected in sequencing libraries prepared by hybridization-capture, but there has been comparatively little attention given to CNA assessment in...

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Dades bibliogràfiques
Publicat a:J Mol Diagn
Autors principals: Grasso, Catherine, Butler, Timothy, Rhodes, Katherine, Quist, Michael, Neff, Tanaya L., Moore, Stephen, Tomlins, Scott A., Reinig, Erica, Beadling, Carol, Andersen, Mark, Corless, Christopher L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707205/
https://ncbi.nlm.nih.gov/pubmed/25468433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2014.09.008
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