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Control-free calling of copy number alterations in deep-sequencing data using GC-content normalization
Summary: We present a tool for control-free copy number alteration (CNA) detection using deep-sequencing data, particularly useful for cancer studies. The tool deals with two frequent problems in the analysis of cancer deep-sequencing data: absence of control sample and possible polyploidy of cancer...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018818/ https://ncbi.nlm.nih.gov/pubmed/21081509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq635 |
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