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SV-Bay: structural variant detection in cancer genomes using a Bayesian approach with correction for GC-content and read mappability

Motivation: Whole genome sequencing of paired-end reads can be applied to characterize the landscape of large somatic rearrangements of cancer genomes. Several methods for detecting structural variants with whole genome sequencing data have been developed. So far, none of these methods has combined...

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Veröffentlicht in:Bioinformatics
Hauptverfasser: Iakovishina, Daria, Janoueix-Lerosey, Isabelle, Barillot, Emmanuel, Regnier, Mireille, Boeva, Valentina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896370/
https://ncbi.nlm.nih.gov/pubmed/26740523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv751
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