Learning smoothing models of copy number profiles using breakpoint annotations

BACKGROUND: Many models have been proposed to detect copy number alterations in chromosomal copy number profiles, but it is usually not obvious to decide which is most effective for a given data set. Furthermore, most methods have a smoothing parameter that determines the number of breakpoints and m...

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Hlavní autoři: Hocking, Toby Dylan, Schleiermacher, Gudrun, Janoueix-Lerosey, Isabelle, Boeva, Valentina, Cappo, Julie, Delattre, Olivier, Bach, Francis, Vert, Jean-Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712326/
https://ncbi.nlm.nih.gov/pubmed/23697330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-164
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