Molecular architecture of photoreceptor phosphodiesterase elucidated by chemical cross-linking and integrative modeling

Photoreceptor phosphodiesterase (PDE6) is the central effector enzyme in visual excitation pathway in rod and cone photoreceptors. Its tight regulation is essential for the speed, sensitivity, recovery and adaptation of visual detection. Although major steps in the PDE6 activation/deactivation pathw...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Zeng-Elmore, Xiaohui, Gao, Xiong-Zhuo, Pellarin, Riccardo, Schneidman-Duhovny, Dina, Zhang, Xiu-Jun, Kozacka, Katie A., Tang, Yang, Sali, Andrej, Chalkley, Robert J., Cote, Rick H., Chu, Feixia
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253074/
https://ncbi.nlm.nih.gov/pubmed/25149264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.07.033
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