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Allosteric regulation of rod photoreceptor phosphodiesterase 6 (PDE6) elucidated by chemical cross-linking and quantitative mass spectrometry
Photoreceptor phosphodiesterase (PDE6) is the central effector enzyme in the visual excitation pathway in rod and cone photoreceptors. Its tight regulation is essential for the speed, sensitivity, recovery and adaptation of visual signaling. The rod PDE6 holoenzyme (Pαβγ(2)) is composed of a catalyt...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Mol Biol |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6733632/ https://ncbi.nlm.nih.gov/pubmed/31394113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.07.035 |
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