ロード中...

The N termini of the inhibitory γ-subunits of phosphodiesterase-6 (PDE6) from rod and cone photoreceptors differentially regulate transducin-mediated PDE6 activation

Phosphodiesterase-6 (PDE6) plays a central role in both rod and cone phototransduction pathways. In the dark, PDE6 activity is suppressed by its inhibitory γ-subunit (Pγ). Rhodopsin-catalyzed activation of the G protein transducin relieves this inhibition and enhances PDE6 catalysis. We hypothesized...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Wang, Xin, Plachetzki, David C., Cote, Rick H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544851/
https://ncbi.nlm.nih.gov/pubmed/30962282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007520
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!