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Complementary Interactions of the Rod PDE6 Inhibitory Subunit with the Catalytic Subunits and Transducin

Activation of the cyclic GMP phosphodiesterase (PDE6) by transducin is the central event of visual signal transduction. How the PDE6 inhibitory γ-subunit (Pγ) interacts with the catalytic subunits (Pαβ) and the transducin α-subunit (α(t)) in this process is not entirely clear. Here we have investiga...

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Detalhes bibliográficos
Main Authors: Guo, Lian-Wang, Hajipour, Abdol R., Ruoho, Arnold E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865329/
https://ncbi.nlm.nih.gov/pubmed/20231289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.086116
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