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Complementary Interactions of the Rod PDE6 Inhibitory Subunit with the Catalytic Subunits and Transducin

Activation of the cyclic GMP phosphodiesterase (PDE6) by transducin is the central event of visual signal transduction. How the PDE6 inhibitory γ-subunit (Pγ) interacts with the catalytic subunits (Pαβ) and the transducin α-subunit (α(t)) in this process is not entirely clear. Here we have investiga...

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Hlavní autoři: Guo, Lian-Wang, Hajipour, Abdol R., Ruoho, Arnold E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865329/
https://ncbi.nlm.nih.gov/pubmed/20231289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.086116
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