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Direct Allosteric Regulation between the GAF Domain and Catalytic Domain of Photoreceptor Phosphodiesterase PDE6

Photoreceptor cGMP phosphodiesterase (PDE6) is the central enzyme in the visual transduction cascade. The PDE6 catalytic subunit contains a catalytic domain and regulatory GAF domains. Unlike most GAF domain-containing cyclic nucleotide phosphodiesterases, little is known about direct allosteric com...

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Bibliografiske detaljer
Main Authors: Zhang, Xiu-Jun, Cahill, Karyn B., Elfenbein, Arye, Arshavsky, Vadim Y., Cote, Rick H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573074/
https://ncbi.nlm.nih.gov/pubmed/18779324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803948200
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