BMP4 Increases the Expression of TRPC and Basal [Ca(2+)](i) via the p38MAPK and ERK1/2 Pathways Independent of BMPRII in PASMCs

Multiple abnormalities of bone morphogenetic protein (BMPs) signaling are implicated in the process of pulmonary arterial hypertension (PAH). BMP4 plays an important role during the process of pulmonary arterial remodeling and mutant of the principle BMP4 receptor, BMP receptors II (BMPRII), is foun...

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Vydáno v:PLoS One
Hlavní autoři: Zhang, Yi, Wang, Yingfeng, Yang, Kai, Tian, Lichun, Fu, Xin, Wang, Yan, Sun, Yueqian, Jiang, Qian, Lu, Wenju, Wang, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251900/
https://ncbi.nlm.nih.gov/pubmed/25461595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112695
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