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Chronic Hypoxia Increases TRPC6 Expression and Basal Intracellular Ca(2+) Concentration in Rat Distal Pulmonary Venous Smooth Muscle

BACKGROUND: Hypoxia causes remodeling and contractile responses in both pulmonary artery (PA) and pulmonary vein (PV). Here we explore the effect of hypoxia on PV and pulmonary venous smooth muscle cells (PVSMCs). METHODS: Chronic hypoxic pulmonary hypertension (CHPH) model was established by exposi...

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Publicat a:PLoS One
Autors principals: Xu, Lei, Chen, Yuqin, Yang, Kai, Wang, Yingfeng, Tian, Lichun, Zhang, Jie, Wang, Elizabeth Wenqian, Sun, Dejun, Lu, Wenju, Wang, Jian
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218830/
https://ncbi.nlm.nih.gov/pubmed/25365342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112007
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