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Bone morphogenetic protein 2 decreases TRPC expression, store-operated Ca(2+) entry, and basal [Ca(2+)](i) in rat distal pulmonary arterial smooth muscle cells

Recent studies indicate that multiple bone morphogenetic protein (BMP) family ligands and receptors are involved in the development of pulmonary arterial hypertension, yet the underlying mechanisms are incompletely understood. Although BMP2 and BMP4 share high homology in amino acid sequence, they a...

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Main Authors: Zhang, Yi, Lu, Wenju, Yang, Kai, Xu, Lei, Lai, Ning, Tian, Lichun, Jiang, Qian, Duan, Xin, Chen, Minsheng, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651608/
https://ncbi.nlm.nih.gov/pubmed/23447035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00036.2012
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