BMP4 Increases the Expression of TRPC and Basal [Ca(2+)](i) via the p38MAPK and ERK1/2 Pathways Independent of BMPRII in PASMCs

Multiple abnormalities of bone morphogenetic protein (BMPs) signaling are implicated in the process of pulmonary arterial hypertension (PAH). BMP4 plays an important role during the process of pulmonary arterial remodeling and mutant of the principle BMP4 receptor, BMP receptors II (BMPRII), is foun...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Zhang, Yi, Wang, Yingfeng, Yang, Kai, Tian, Lichun, Fu, Xin, Wang, Yan, Sun, Yueqian, Jiang, Qian, Lu, Wenju, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251900/
https://ncbi.nlm.nih.gov/pubmed/25461595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112695
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