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Coupled Protein Diffusion and Folding in the Cell

When a protein unfolds in the cell, its diffusion coefficient is affected by its increased hydrodynamic radius and by interactions of exposed hydrophobic residues with the cytoplasmic matrix, including chaperones. We characterize protein diffusion by photobleaching whole cells at a single point, and...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Guo, Minghao, Gelman, Hannah, Gruebele, Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249841/
https://ncbi.nlm.nih.gov/pubmed/25436502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113040
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