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The Diffusion Coefficient for PGK Folding in Eukaryotic Cells

We compare the folding kinetics of a fluorescent phosphoglycerate kinase construct in 30 mammalian cells with that in aqueous buffer. In both environments, the kinetics can be fitted to the functional form exp[−(t/τ)(β)]. A histogram of τ shows that the average folding relaxation time in cells is on...

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Detalhes bibliográficos
Main Authors: Dhar, Apratim, Ebbinghaus, Simon, Shen, Zhen, Mishra, Tripta, Gruebele, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965994/
https://ncbi.nlm.nih.gov/pubmed/21044564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.066
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