Protein Stability and Folding Kinetics in the Nucleus and Endoplasmic Reticulum of Eucaryotic Cells

We measure the stability and folding relaxation rate of phosphoglycerate kinase (PGK) Förster resonance energy transfer (FRET) constructs localized in the nucleus or in the endoplasmic reticulum (ER) of eukaryotic cells. PGK has a more compact native state in the cellular compartments than in aqueou...

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Détails bibliographiques
Auteurs principaux: Dhar, A., Girdhar, K., Singh, D., Gelman, H., Ebbinghaus, S., Gruebele, M.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2011
Sujets:
Protein
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136782/
https://ncbi.nlm.nih.gov/pubmed/21767495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.05.071
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