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Coupled Protein Diffusion and Folding in the Cell

When a protein unfolds in the cell, its diffusion coefficient is affected by its increased hydrodynamic radius and by interactions of exposed hydrophobic residues with the cytoplasmic matrix, including chaperones. We characterize protein diffusion by photobleaching whole cells at a single point, and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Guo, Minghao, Gelman, Hannah, Gruebele, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249841/
https://ncbi.nlm.nih.gov/pubmed/25436502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113040
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