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The extracellular protein VlsE is destabilized inside cells

We use U2OS cells as in vivo ‘test tubes’ to study how the same cytoplasmic environment has opposite effects on the stability of two different proteins. Protein folding stability and kinetics were compared by Fast Relaxation Imaging (FReI), which combines a temperature jump with fluorescence microsc...

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Autors principals: Guzman, Irisbel, Gelman, Hannah, Tai, Jonathan, Gruebele, Martin
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059009/
https://ncbi.nlm.nih.gov/pubmed/24013077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.08.024
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