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The extracellular protein VlsE is destabilized inside cells

We use U2OS cells as in vivo ‘test tubes’ to study how the same cytoplasmic environment has opposite effects on the stability of two different proteins. Protein folding stability and kinetics were compared by Fast Relaxation Imaging (FReI), which combines a temperature jump with fluorescence microsc...

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Autores principales: Guzman, Irisbel, Gelman, Hannah, Tai, Jonathan, Gruebele, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059009/
https://ncbi.nlm.nih.gov/pubmed/24013077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.08.024
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