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Coupled Protein Diffusion and Folding in the Cell

When a protein unfolds in the cell, its diffusion coefficient is affected by its increased hydrodynamic radius and by interactions of exposed hydrophobic residues with the cytoplasmic matrix, including chaperones. We characterize protein diffusion by photobleaching whole cells at a single point, and...

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Bibliographic Details
Published in:PLoS One
Main Authors: Guo, Minghao, Gelman, Hannah, Gruebele, Martin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249841/
https://ncbi.nlm.nih.gov/pubmed/25436502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113040
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