Maternal Intravenous Administration of Azithromycin Results in Significant Fetal Uptake in a Sheep Model of Second Trimester Pregnancy

Treatment of intrauterine infection is likely key to preventing a significant proportion of preterm deliveries before 32 weeks of gestation. Azithromycin (AZ) may be an effective antimicrobial in pregnancy; however, few gestation age-approriate data are available to inform the design of AZ-based tre...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Kemp, Matthew W., Miura, Yuichiro, Payne, Matthew S., Jobe, Alan H., Kallapur, Suhas G., Saito, Masatoshi, Stock, Sarah J., Spiller, O. Brad, Ireland, Demelza J., Yaegashi, Nobuo, Clarke, Michael, Hahne, Dorothee, Rodger, Jennifer, Keelan, Jeffrey A., Newnham, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249365/
https://ncbi.nlm.nih.gov/pubmed/25155606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03721-14
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