Maternal Intravenous Administration of Azithromycin Results in Significant Fetal Uptake in a Sheep Model of Second Trimester Pregnancy

Treatment of intrauterine infection is likely key to preventing a significant proportion of preterm deliveries before 32 weeks of gestation. Azithromycin (AZ) may be an effective antimicrobial in pregnancy; however, few gestation age-approriate data are available to inform the design of AZ-based tre...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Kemp, Matthew W., Miura, Yuichiro, Payne, Matthew S., Jobe, Alan H., Kallapur, Suhas G., Saito, Masatoshi, Stock, Sarah J., Spiller, O. Brad, Ireland, Demelza J., Yaegashi, Nobuo, Clarke, Michael, Hahne, Dorothee, Rodger, Jennifer, Keelan, Jeffrey A., Newnham, John P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249365/
https://ncbi.nlm.nih.gov/pubmed/25155606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03721-14
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