Maternal Intravenous Treatment with either Azithromycin or Solithromycin Clears Ureaplasma parvum from the Amniotic Fluid in an Ovine Model of Intrauterine Infection

Intrauterine infection with Ureaplasma spp. is strongly associated with preterm birth and adverse neonatal outcomes. We assessed whether combined intraamniotic (IA) and maternal intravenous (IV) treatment with one of two candidate antibiotics, azithromycin (AZ) or solithromycin (SOLI), would eradica...

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Bibliografiske detaljer
Main Authors: Miura, Yuichiro, Payne, Matthew S., Keelan, Jeffrey A., Noe, Andres, Carter, Sean, Watts, Rory, Spiller, Owen B., Jobe, Alan H., Kallapur, Suhas G., Saito, Masatoshi, Stock, Sarah J., Newnham, John P., Kemp, Matthew W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135857/
https://ncbi.nlm.nih.gov/pubmed/24982089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03187-14
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