Maternal Intravenous Treatment with either Azithromycin or Solithromycin Clears Ureaplasma parvum from the Amniotic Fluid in an Ovine Model of Intrauterine Infection

Intrauterine infection with Ureaplasma spp. is strongly associated with preterm birth and adverse neonatal outcomes. We assessed whether combined intraamniotic (IA) and maternal intravenous (IV) treatment with one of two candidate antibiotics, azithromycin (AZ) or solithromycin (SOLI), would eradica...

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Main Authors: Miura, Yuichiro, Payne, Matthew S., Keelan, Jeffrey A., Noe, Andres, Carter, Sean, Watts, Rory, Spiller, Owen B., Jobe, Alan H., Kallapur, Suhas G., Saito, Masatoshi, Stock, Sarah J., Newnham, John P., Kemp, Matthew W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135857/
https://ncbi.nlm.nih.gov/pubmed/24982089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03187-14
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