Maternal Intravenous Administration of Azithromycin Results in Significant Fetal Uptake in a Sheep Model of Second Trimester Pregnancy

Treatment of intrauterine infection is likely key to preventing a significant proportion of preterm deliveries before 32 weeks of gestation. Azithromycin (AZ) may be an effective antimicrobial in pregnancy; however, few gestation age-approriate data are available to inform the design of AZ-based tre...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Kemp, Matthew W., Miura, Yuichiro, Payne, Matthew S., Jobe, Alan H., Kallapur, Suhas G., Saito, Masatoshi, Stock, Sarah J., Spiller, O. Brad, Ireland, Demelza J., Yaegashi, Nobuo, Clarke, Michael, Hahne, Dorothee, Rodger, Jennifer, Keelan, Jeffrey A., Newnham, John P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2014
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249365/
https://ncbi.nlm.nih.gov/pubmed/25155606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03721-14
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