Maternal Intravenous Administration of Azithromycin Results in Significant Fetal Uptake in a Sheep Model of Second Trimester Pregnancy

Treatment of intrauterine infection is likely key to preventing a significant proportion of preterm deliveries before 32 weeks of gestation. Azithromycin (AZ) may be an effective antimicrobial in pregnancy; however, few gestation age-approriate data are available to inform the design of AZ-based tre...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Kemp, Matthew W., Miura, Yuichiro, Payne, Matthew S., Jobe, Alan H., Kallapur, Suhas G., Saito, Masatoshi, Stock, Sarah J., Spiller, O. Brad, Ireland, Demelza J., Yaegashi, Nobuo, Clarke, Michael, Hahne, Dorothee, Rodger, Jennifer, Keelan, Jeffrey A., Newnham, John P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249365/
https://ncbi.nlm.nih.gov/pubmed/25155606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03721-14
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