Maternal Intravenous Administration of Azithromycin Results in Significant Fetal Uptake in a Sheep Model of Second Trimester Pregnancy

Treatment of intrauterine infection is likely key to preventing a significant proportion of preterm deliveries before 32 weeks of gestation. Azithromycin (AZ) may be an effective antimicrobial in pregnancy; however, few gestation age-approriate data are available to inform the design of AZ-based tre...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kemp, Matthew W., Miura, Yuichiro, Payne, Matthew S., Jobe, Alan H., Kallapur, Suhas G., Saito, Masatoshi, Stock, Sarah J., Spiller, O. Brad, Ireland, Demelza J., Yaegashi, Nobuo, Clarke, Michael, Hahne, Dorothee, Rodger, Jennifer, Keelan, Jeffrey A., Newnham, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249365/
https://ncbi.nlm.nih.gov/pubmed/25155606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03721-14
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