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Blockade of Indoleamine 2,3-Dioxygenase Reduces Mortality from Peritonitis and Sepsis in Mice by Regulating Functions of CD11b(+) Peritoneal Cells

Indoleamine 2,3-dioxygenase-1 (Ido), which catalyzes the first and limiting step of tryptophan catabolism, has been implicated in immune tolerance. However, the roles of Ido in systemic bacterial infection are complicated and remain controversial. To explore this issue, we examined the roles of Ido...

詳細記述

保存先:
書誌詳細
出版年:Infect Immun
主要な著者: Hoshi, Masato, Osawa, Yosuke, Ito, Hiroyasu, Ohtaki, Hirofumi, Ando, Tatsuya, Takamatsu, Manabu, Hara, Akira, Saito, Kuniaki, Seishima, Mitsuru
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249307/
https://ncbi.nlm.nih.gov/pubmed/25114116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02113-14
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