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Inhibition of indoleamine 2,3-dioxygenase activity enhances the anti-tumour effects of a Toll-like receptor 7 agonist in an established cancer model

Toll-like receptor (TLR) agonists have been shown to have anti-tumour activity in basic research and clinical studies. However, TLR agonist monotherapy does not sufficiently eliminate tumours. Activation of the innate immune response by TLR agonists is effective at driving adaptive immunity via inte...

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Bibliografski detalji
Izdano u:Immunology
Glavni autori: Ito, Hiroyasu, Ando, Tatsuya, Arioka, Yuko, Saito, Kuniaki, Seishima, Mitsuru
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368168/
https://ncbi.nlm.nih.gov/pubmed/25322876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12413
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