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Inhibition of indoleamine 2,3-dioxygenase activity enhances the anti-tumour effects of a Toll-like receptor 7 agonist in an established cancer model

Toll-like receptor (TLR) agonists have been shown to have anti-tumour activity in basic research and clinical studies. However, TLR agonist monotherapy does not sufficiently eliminate tumours. Activation of the innate immune response by TLR agonists is effective at driving adaptive immunity via inte...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Immunology
Κύριοι συγγραφείς: Ito, Hiroyasu, Ando, Tatsuya, Arioka, Yuko, Saito, Kuniaki, Seishima, Mitsuru
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BlackWell Publishing Ltd 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368168/
https://ncbi.nlm.nih.gov/pubmed/25322876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12413
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