The Role of Indoleamine 2,3-Dioxygenase in Diethylnitrosamine-Induced Liver Carcinogenesis

Indoleamine 2,3-dioxygenase (IDO), a tryptophan-catabolizing intracellular enzyme of the L-kynurenine pathway, causes preneoplastic cells and tumor cells to escape the immune system by inducing immune tolerance; this mechanism might be associated with the development and progression of human maligna...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Shibata, Yuhei, Hara, Takeshi, Nagano, Junji, Nakamura, Nobuhiko, Ohno, Tomohiko, Ninomiya, Soranobu, Ito, Hiroyasu, Tanaka, Takuji, Saito, Kuniaki, Seishima, Mitsuru, Shimizu, Masahito, Moriwaki, Hisataka, Tsurumi, Hisashi
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699706/
https://ncbi.nlm.nih.gov/pubmed/26727596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146279
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