Effects of Indoleamine 2,3-Dioxygenase Deficiency on High-Fat Diet-Induced Hepatic Inflammation

Hepatic immune regulation is associated with the progression from simple steatosis to non-alcoholic steatohepatitis, a severe condition of inflamed fatty liver. Indoleamine 2,3-dioxygenase (IDO), an intracellular enzyme that mediates the catabolism of L-tryptophan to L-kynurenine, plays an important...

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Autors principals: Nagano, Junji, Shimizu, Masahito, Hara, Takeshi, Shirakami, Yohei, Kochi, Takahiro, Nakamura, Nobuhiko, Ohtaki, Hirofumi, Ito, Hiroyasu, Tanaka, Takuji, Tsurumi, Hisashi, Saito, Kuniaki, Seishima, Mitsuru, Moriwaki, Hisataka
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767792/
https://ncbi.nlm.nih.gov/pubmed/24039933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073404
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