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Induction of hepatitis B virus surface antigen-specific cytotoxic T lymphocytes can be up-regulated by the inhibition of indoleamine 2, 3-dioxygenase activity

Cytotoxic T lymphocytes (CTLs) are thought to be major effectors involved in viral clearance during acute infections, including hepatitis B virus (HBV) infection. A persistent HBV infection is characterized by a lack of or a weak CTL response to HBV, which may be reflective of tolerance to HBV. Effi...

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Detalhes bibliográficos
Main Authors: Ito, Hiroyasu, Ando, Tatsuya, Ando, Kazuki, Ishikawa, Tetsuya, Saito, Kuniaki, Moriwaki, Hisataka, Seishima, Mitsuru
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107671/
https://ncbi.nlm.nih.gov/pubmed/24580128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12274
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