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Blockade of Indoleamine 2,3-Dioxygenase Reduces Mortality from Peritonitis and Sepsis in Mice by Regulating Functions of CD11b(+) Peritoneal Cells

Indoleamine 2,3-dioxygenase-1 (Ido), which catalyzes the first and limiting step of tryptophan catabolism, has been implicated in immune tolerance. However, the roles of Ido in systemic bacterial infection are complicated and remain controversial. To explore this issue, we examined the roles of Ido...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Infect Immun
Κύριοι συγγραφείς: Hoshi, Masato, Osawa, Yosuke, Ito, Hiroyasu, Ohtaki, Hirofumi, Ando, Tatsuya, Takamatsu, Manabu, Hara, Akira, Saito, Kuniaki, Seishima, Mitsuru
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249307/
https://ncbi.nlm.nih.gov/pubmed/25114116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02113-14
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