Blockade of Indoleamine 2,3-Dioxygenase Reduces Mortality from Peritonitis and Sepsis in Mice by Regulating Functions of CD11b(+) Peritoneal Cells

Indoleamine 2,3-dioxygenase-1 (Ido), which catalyzes the first and limiting step of tryptophan catabolism, has been implicated in immune tolerance. However, the roles of Ido in systemic bacterial infection are complicated and remain controversial. To explore this issue, we examined the roles of Ido...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Infect Immun
Egile Nagusiak: Hoshi, Masato, Osawa, Yosuke, Ito, Hiroyasu, Ohtaki, Hirofumi, Ando, Tatsuya, Takamatsu, Manabu, Hara, Akira, Saito, Kuniaki, Seishima, Mitsuru
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Host Response and Inflammation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249307/
https://ncbi.nlm.nih.gov/pubmed/25114116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02113-14
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