An Absence of Nuclear Lamins in Keratinocytes Leads to Ichthyosis, Defective Epidermal Barrier Function, and Intrusion of Nuclear Membranes and Endoplasmic Reticulum into the Nuclear Chromatin

B-type lamins (lamins B1 and B2) have been considered to be essential for many crucial functions in the cell nucleus (e.g., DNA replication and mitotic spindle formation). However, this view has been challenged by the observation that an absence of both B-type lamins in keratinocytes had no effect o...

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Bibliografiska uppgifter
I publikationen:Mol Cell Biol
Huvudupphovsmän: Jung, Hea-Jin, Tatar, Angelica, Tu, Yiping, Nobumori, Chika, Yang, Shao H., Goulbourne, Chris N., Herrmann, Harald, Fong, Loren G., Young, Stephen G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248738/
https://ncbi.nlm.nih.gov/pubmed/25312645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00997-14
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