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Systemic DNA damage responses: Organismal adaptations to genome instability
DNA damage checkpoints are important tumor suppressor mechanisms that halt cell cycle progression to allow time for DNA repair, or induce senescence and apoptosis to permanently remove damaged cells. Non-cell-autonomous DNA damage responses activate the innate immune system in multiple metazoan spec...
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| 出版年: | Trends Genet |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4248340/ https://ncbi.nlm.nih.gov/pubmed/24439457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2013.12.001 |
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