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Systemic DNA damage responses in aging and diseases

The genome is constantly attacked by a variety of genotoxic insults. The causal role for DNA damage in aging and cancer is exemplified by genetic defects in DNA repair that underlie a broad spectrum of acute and chronic human disorders that are characterized by developmental abnormalities, premature...

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Detalhes bibliográficos
Publicado no:Semin Cancer Biol
Main Authors: Ribezzo, Flavia, Shiloh, Yosef, Schumacher, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886830/
https://ncbi.nlm.nih.gov/pubmed/26773346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2015.12.005
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