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The p53 network: Cellular and systemic DNA damage responses in aging and cancer
Genome instability contributes to cancer development and accelerates age-related pathologies as evidenced by a variety of congenital cancer susceptibility and progeroid syndromes that are caused by defects in genome maintenance mechanisms. DNA damage response pathways that are mediated through the t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4120491/ https://ncbi.nlm.nih.gov/pubmed/22265392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2011.12.002 |
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