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DNA damage responses and p53 in the aging process

The genome is constantly attacked by genotoxic insults. DNA damage has long been established to cause cancer development through its mutagenic consequences. Conversely, DNA damage is induced during radiation- and chemotherapy to drive cells into apoptosis or senescence as outcomes of the DNA damage...

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Библиографические подробности
Опубликовано в: :Blood
Главные авторы: Ou, Hui-Ling, Schumacher, Björn
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839964/
https://ncbi.nlm.nih.gov/pubmed/29141944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-746396
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