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DNA damage responses and p53 in the aging process

The genome is constantly attacked by genotoxic insults. DNA damage has long been established to cause cancer development through its mutagenic consequences. Conversely, DNA damage is induced during radiation- and chemotherapy to drive cells into apoptosis or senescence as outcomes of the DNA damage...

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Podrobná bibliografie
Vydáno v:Blood
Hlavní autoři: Ou, Hui-Ling, Schumacher, Björn
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839964/
https://ncbi.nlm.nih.gov/pubmed/29141944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-746396
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