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Quality control mechanisms in cellular and systemic DNA damage responses
The maintenance of the genome is of pivotal importance for the functional integrity of cells and tissues. The gradual accumulation of DNA damage is thought to contribute to the functional decline of tissues and organs with ageing. Defects in multiple genome maintenance systems cause human disorders...
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| Pubblicato in: | Ageing Res Rev |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886828/ https://ncbi.nlm.nih.gov/pubmed/25560147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2014.12.009 |
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