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DNA damage in germ cells induces immune response triggering systemic stress resistance
DNA damage responses have been well characterized in their cell-autonomous checkpoint functions leading to cell cycle arrest, senescence, and apoptosis (1). In contrast, systemic responses to tissue-specific genome instability remain poorly understood. In adult C. elegans worms germ cells undergo mi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4120807/ https://ncbi.nlm.nih.gov/pubmed/23975097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12452 |
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