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The p53 network: Cellular and systemic DNA damage responses in aging and cancer

Genome instability contributes to cancer development and accelerates age-related pathologies as evidenced by a variety of congenital cancer susceptibility and progeroid syndromes that are caused by defects in genome maintenance mechanisms. DNA damage response pathways that are mediated through the t...

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Sonraí Bibleagrafaíochta
Main Authors: Reinhardt, H. Christian, Schumacher, Björn
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120491/
https://ncbi.nlm.nih.gov/pubmed/22265392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2011.12.002
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