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Systemic DNA damage responses: Organismal adaptations to genome instability
DNA damage checkpoints are important tumor suppressor mechanisms that halt cell cycle progression to allow time for DNA repair, or induce senescence and apoptosis to permanently remove damaged cells. Non-cell-autonomous DNA damage responses activate the innate immune system in multiple metazoan spec...
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| Publicat a: | Trends Genet |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4248340/ https://ncbi.nlm.nih.gov/pubmed/24439457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2013.12.001 |
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